Titin is an extraordinarily long, flexible, and slender myofibrillar protein.

  title={Titin is an extraordinarily long, flexible, and slender myofibrillar protein.},
  author={K Wang and Ruben Ramirez-Mitchell and D. C. Palter},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={81 12},
" Titin " is a term used to describe a pair of closely related megadalton polypeptides that together are the third most abundant myofibrillar protein in a wide range of striated muscles. It has been proposed that titin and another giant protein, nebulin , are the major components of an elastic cytoskeletal lattice within the sarcomere. We have now purified the leading band, titin -2 (T2), of the titin doublet in native forms by extraction with Guba -Straub solution followed by chromatography… 

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