Titanium nanotubes activate genes related to bone formation in vitro

@inproceedings{Pozio2012TitaniumNA,
  title={Titanium nanotubes activate genes related to bone formation in vitro},
  author={Alfonso Pozio and Annalisa Palmieri and Ambra Girardi and Francesca Maria Cura and Francesco Carinci},
  booktitle={Dental research journal},
  year={2012}
}
BACKGROUND Titanium is used worldwide to make osseointegrable devices, thanks to its favorable characteristics as mechanical proprieties and biocompatibility, demonstrated by in vivo studies with animal models and clinical trials over a forty-year period. However, the exact genetic effect of the titanium layer on cells is still not well characterized. MATERIALS AND METHODS To investigate how titanium nanotubes stimulate osteoblasts differentiation and proliferation, some osteoblast genes (SP7… CONTINUE READING

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