Tissue tropisms, infection kinetics, histologic lesions, and antibody response of the MR766 strain of Zika virus in a murine model

@inproceedings{Kawiecki2017TissueTI,
  title={Tissue tropisms, infection kinetics, histologic lesions, and antibody response of the MR766 strain of Zika virus in a murine model},
  author={Anna B. Kawiecki and E. Handly Mayton and M. Fausta Dutuze and Brad A. Goupil and Ingeborg Maria Langohr and Fabio del Piero and Rebecca C Christofferson},
  booktitle={Virology Journal},
  year={2017}
}
The appearance of severe Zika virus (ZIKV) disease in the most recent outbreak has prompted researchers to respond through the development of tools to quickly characterize transmission and pathology. We describe here another such tool, a mouse model of ZIKV infection and pathogenesis using the MR766 strain of virus that adds to the growing body of knowledge regarding ZIKV kinetics in small animal models. We infected mice with the MR766 strain of ZIKV to determine infection kinetics via serum… CONTINUE READING