Tissue transglutaminase expression in celiac mucosa: an immunohistochemical study

@article{Gorgun2009TissueTE,
  title={Tissue transglutaminase expression in celiac mucosa: an immunohistochemical study},
  author={Julia Gorgun and Anna Portyanko and Yuri Marakhouski and Eugeni Cherstvoy},
  journal={Virchows Archiv},
  year={2009},
  volume={455},
  pages={363-373}
}
Tissue transglutaminase (tTG) constitutes the main autoantigen in celiac disease (CD). The aim of the study was to clarify weather celiac disease is associated with changes in tTG expression in duodenal mucosa. Tissue transglutaminase was assessed immunohistochemically (clone CUB 7402) in duodenal biopsy specimens from 22 untreated CD patients, ten normal controls (NC) with unremarkable duodenal mucosa, and nine disease nonceliac controls (DC). In 15 CD patients duodenal biopsy specimens were… CONTINUE READING