Tissue stroma as a regulator of leukocyte recruitment in inflammation.

@article{McGettrick2012TissueSA,
  title={Tissue stroma as a regulator of leukocyte recruitment in inflammation.},
  author={Helen M McGettrick and Lynn M Butler and Chris D. Buckley and G Ed Rainger and Gerard B Nash},
  journal={Journal of leukocyte biology},
  year={2012},
  volume={91 3},
  pages={
          385-400
        }
}
The stromal milieu (cellular and matrix components) helps establish tissue "address-codes" that direct leukocyte behavior in inflamed tissue. Coordinated interactions among the stroma, leukocytes, and ECs dictate which leukocytes are recruited, whether they are retained within the inflamed site, and how long they survive. Herein, we discuss how the stromal milieu influences the leukocyte recruitment cascade. Moreover, we explore how corruption of the stromal phenotype in chronic inflammatory… CONTINUE READING

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