Tissue specificity, localization in brain, and cell-free translation of mRNA encoding the A3 isoform of Na+,K+-ATPase.

@article{Schneider1988TissueSL,
  title={Tissue specificity, localization in brain, and cell-free translation of mRNA encoding the A3 isoform of Na+,K+-ATPase.},
  author={Jay W. Schneider and Robert W. Mercer and Maureen Gilmore-Hebert and Manuel F. Utset and Cary Lai and Andrea L Greene and Edward J. Benz},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1988},
  volume={85 1},
  pages={284-8}
}
The isolation of multiple Na+,K+-ATPase cDNAs from rat brain has led to the discovery of a family of alpha-isoform genes. Using A1 (alpha), A2 (alpha+), and A3 (alpha III) Na+,K+-ATPase gene probes, we have analyzed the distribution of Na+,K+-ATPase mRNAs in adult and fetal rat tissues by RNA blot and hybridization histochemistry. A1 Na+,K+-ATPase mRNA was found ubiquitously among various tissues, with highest levels in transport epithelial and neural tissues. A2 mRNA was found in adult neural… CONTINUE READING

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