Tissue-specific gene expression and ecdysone-regulated genomic networks in Drosophila.

@article{Li2003TissuespecificGE,
  title={Tissue-specific gene expression and ecdysone-regulated genomic networks in Drosophila.},
  author={Tong-Ruei Li and Kevin P White},
  journal={Developmental cell},
  year={2003},
  volume={5 1},
  pages={59-72}
}
During insect metamorphosis, each tissue displays a unique physiological and morphological response to the steroid hormone 20-hydroxyecdysone (ecdysone). We assayed gene expression in five tissues during metamorphosis onset. Larval-specific tissues display major changes in genome-wide expression profiles, whereas tissues that survive into adulthood display few changes. In one larval tissue, the salivary gland, we used a computational approach to identify a regulatory motif and a cognate… CONTINUE READING
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