Tissue-specific expression in mammalian brain, heart, and muscle of S1, a member of the elongation factor-1 alpha gene family.

@article{Lee1992TissuespecificEI,
  title={Tissue-specific expression in mammalian brain, heart, and muscle of S1, a member of the elongation factor-1 alpha gene family.},
  author={Seung-Hwan Lee and Aline Francoeur and Shi-qing Liu and Erming Wang},
  journal={The Journal of biological chemistry},
  year={1992},
  volume={267 33},
  pages={
          24064-8
        }
}
Elongation factor-1 alpha (EF-1 alpha) is an ubiquitous protein that functions in peptide elongation during mRNA translation. We previously reported the isolation of a rat S1 protein that is antigenically related to statin, a nonproliferation-specific protein; this S1 gene shares a high degree of homology to EF-1 alpha. We constructed specific riboprobes to the two genes, based on the difference in the 3' noncoding regions of both S1 and EF-1 alpha mRNAs. Northern analysis and RNase protection… CONTINUE READING

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