Tissue-specific differences in mRNA quantification of glucose transporter 1 and vascular endothelial growth factor with special regard to death investigations of fatal injuries.

@article{Zhao2008TissuespecificDI,
  title={Tissue-specific differences in mRNA quantification of glucose transporter 1 and vascular endothelial growth factor with special regard to death investigations of fatal injuries.},
  author={Dong Zhao and Takaki Ishikawa and L H Quan and Dong-Ri Li and Tomomi Michiue and Chiemi Yoshida and Ayumi Komatu and Jian-hua Chen and Baoli Zhu and Hitoshi Maeda},
  journal={Forensic science international},
  year={2008},
  volume={177 2-3},
  pages={
          176-83
        }
}
Glucose transporter 1 (GLUT1) and vascular endothelial growth factor (VEGF) have been established as being responsible for cellular adaptation to oxygen deficiency in tissue ischemia and hypoxia mediated by hypoxia-inducible factor 1. We hypothesized that mRNA quantification of these factors in autopsy tissue specimens could have diagnostic significance for investigating the pathology of death, especially after injury. Various cases (total, n=119; less than 48h postmortem) were examined… CONTINUE READING

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