Tissue self-organization based on collective cell migration by contact activation of locomotion and chemotaxis

@inproceedings{Fujimori2019TissueSB,
  title={Tissue self-organization based on collective cell migration by contact activation of locomotion and chemotaxis},
  author={Taihei Fujimori and Akihiko Nakajima and Nao H. Shimada and Satoshi Sawai},
  booktitle={Proceedings of the National Academy of Sciences of the United States of America},
  year={2019}
}
Despite their central role in multicellular organization, navigation rules that dictate cell rearrangement remain largely undefined. Contact between neighboring cells and diffusive attractant molecules are two of the major determinants of tissue-level patterning; however, in most cases, molecular and developmental complexity hinders one from decoding the exact governing rules of individual cell movement. A primordial example of tissue patterning by cell rearrangement is found in the social… CONTINUE READING

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