Tissue responses in experimental schistosomiasis japonica in the pig: a histopathologic study of different stages of single low- or high-dose infections.

@article{Hurst2000TissueRI,
  title={Tissue responses in experimental schistosomiasis japonica in the pig: a histopathologic study of different stages of single low- or high-dose infections.},
  author={Maria H Hurst and Amy L Willingham and Ronny Lindberg},
  journal={The American journal of tropical medicine and hygiene},
  year={2000},
  volume={62 1},
  pages={45-56}
}
The tissue responses of pigs exposed to either 100 or 2,000 Schistosoma japonicum cercariae were examined at 4, 11, 17, and 24 weeks postinfection (PI) to explore the pig as an animal model for pathologic aspects of human schistosomiasis japonica. Egg granulomas were present in the liver, intestine, and occasionally in the lungs from 11 weeks PI. There were also many free eggs and early exudative reactions to eggs in the intestine. At 11 weeks PI, pigs in the higher dose group showed marked… CONTINUE READING