Tissue response to facial contour augmentation with dense and porous hydroxylapatite in rhesus monkeys.

@article{Deeb1989TissueRT,
  title={Tissue response to facial contour augmentation with dense and porous hydroxylapatite in rhesus monkeys.},
  author={M E el Deeb and Ralph E. Holmes},
  journal={Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons},
  year={1989},
  volume={47 12},
  pages={1282-9}
}
Using extraoral incisions, subperiosteal pockets were created bilaterally over the zygomatic and mandibular areas in six rhesus monkeys. One side of each anatomic site received a dense block of hydroxylapatite (HA) implant, and the contralateral side received an equivalent-sized block of porous HA implant. Monkeys were killed at 3, 6, and 12 months, and the implants were manually tested for mobility. The implants were then retrieved in block specimens. Half of each specimen was decalcified… CONTINUE READING