Tissue remodelling through branching morphogenesis

@article{Affolter2009TissueRT,
  title={Tissue remodelling through branching morphogenesis},
  author={Markus Affolter and Rolf Zeller and Emmanuel Caussinus},
  journal={Nature Reviews Molecular Cell Biology},
  year={2009},
  volume={10},
  pages={831-842}
}
Branched structures are evident at all levels of organization in living organisms. Many organs, such as the vascular system, lung, kidney and mammary gland, are heavily branched. In each of these cases, equally fascinating questions have been put forward, including those that address the cellular and molecular mechanisms that regulate the branching process itself, such as where the branches are initiated and how they extend and grow in the right direction. Recent experiments suggest that cell… 
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Comparing mechanisms that regulate branching are compared, focusing on how cell cohorts behave in a coordinated manner to build branched tissues.
Extracellular matrix receptors in branched organs.
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The mammary gland undergoes a spectacular series of changes as it develops, and maintains a remarkable capacity to remodel and regenerate for several decades. Mammary morphogenesis has been
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A deterministic, spatio-temporal differential-equation based model of the core signaling network that governs lung branching morphogenesis is developed and it is concluded that the FGF10-SHH-Ptc1 module is sufficient to generate pattern that correspond to the observed branching modes.
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TLDR
It is found that a growth-induced physical instability defines the relative locations of branches within the developing murine airway epithelium in the absence of mesenchyme, suggesting that physical mechanisms can create the biological patterns that underlie tissue morphogenesis in the embryo.
Molecular control of endothelial cell behaviour during blood vessel morphogenesis
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These emerging frameworks controlling angiogenesis provide unique insights into fundamental biological processes common to other systems, such as tissue branching morphogenesis, mechanotransduction and tubulogenesis.
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References

SHOWING 1-10 OF 112 REFERENCES
Tracheal branching morphogenesis in Drosophila: new insights into cell behaviour and organ architecture
TLDR
The similarities and differences between flies and vertebrates in branched organ formation that are becoming apparent are discussed, and the use of high resolution in vivo imaging approaches are reviewed.
Tissue Geometry Determines Sites of Mammary Branching Morphogenesis in Organotypic Cultures
TLDR
The results reveal that tissue geometry can control organ morphogenesis by defining the local cellular microenvironment, a finding that has relevance to control of invasion and metastasis.
Branching morphogenesis.
TLDR
The most important feature in determining the morphology of the tubular systems is the frequency and geometry of branching, and deciphering the molecular mechanisms underlying the sprouting of new branches from preexisting ones is the key to understanding the formation of Tubular systems.
From cells to organs: building polarized tissue
TLDR
This work discusses how conserved polarity complexes, signalling networks, transcription factors, membrane-trafficking pathways, mechanisms for forming lumens in tubes and other hollow structures, and transitions between different types of polarity, such as between epithelial and mesenchymal cells, are used in similar and iterative manners to build all tissues.
Organogenesis: Molecular Mechanisms Of Tubulogenesis
TLDR
A review of tubular systems using examples from both invertebrate and vertebrate systems highlights progress in understanding basic principles and briefly discusses the possible evolution of strategies to regulate the morphogenesis of tubules.
Orchestrating size and shape during morphogenesis
TLDR
Drosophila has proved to be a particularly powerful model system with which to identify the signalling pathways that organize tissue patterns and new models integrate how specific signals and mechanical forces shape tissues and may also control their size.
Architectural patterns in branching morphogenesis in the kidney.
TLDR
During kidney development, several discrete steps generate its three-dimensional pattern including specific branch types, regional differential growth of stems, the specific axes of growth and temporal progression of the pattern, which generates the characteristic shape of the kidney.
Branching morphogenesis of the Drosophila tracheal system.
TLDR
Mapping of the cell movements and shape changes during the sprouting process has revealed that distinct mechanisms of epithelial migration and tube formation are used at each stage of branching, identifying a general program in which a fibroblast growth factor (FGF) and fibro Blast growth factor receptor (FGFR) are used repeatedly to control branch budding and outgrowth.
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