Tissue reaction and material biodegradation of a calcium sulfate/apatite biphasic bone substitute in rat muscle

@inproceedings{Wang2016TissueRA,
  title={Tissue reaction and material biodegradation of a calcium sulfate/apatite biphasic bone substitute in rat muscle},
  author={J Wang and Magnus T{\"a}gil and Hanna Isaksson and Mathias Bostr{\"o}m and Lars Lidgren},
  booktitle={Journal of orthopaedic translation},
  year={2016}
}
Background/Objective A biphasic ceramic bone substitute consisting of calcium sulfate and hydroxyapatite has been reported to give good clinical outcome regarding bone regeneration and may serve as a carrier for antibiotics in the treatment of bone infections. Often, the overlying muscle is in direct contact with the synthetic graft. The dissolving bone substitute induces inflammation, which may be harmful to the surrounding soft and muscle tissue. The aim of the present study was to evaluate… CONTINUE READING

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