Tissue plasminogen activator as an adjuvant therapy for pleural empyema in pediatric patients.

@article{Ray2004TissuePA,
  title={Tissue plasminogen activator as an adjuvant therapy for pleural empyema in pediatric patients.},
  author={Theresa L Ray and John W Berkenbosch and Pierantonio Russo and Joseph Drew Tobias},
  journal={Journal of intensive care medicine},
  year={2004},
  volume={19 1},
  pages={44-50}
}
The authors retrospectively review the clinical course and outcome of 6 pediatric patients, ranging in age from 2 to 13 years, who were treated with TPA for complex empyema. Efficacy was assessed by evaluating pleural fluid drainage for 6 hours prior to and subsequent to each dose of TPA, as well as by resolution of fever and length of hospital stay. The… CONTINUE READING