Tissue microarrays enabling high-throughput molecular pathology.

  title={Tissue microarrays enabling high-throughput molecular pathology.},
  author={Mikiko Takikita and J Y Chung and Stephen M. Hewitt},
  journal={Current opinion in biotechnology},
  volume={18 4},
The tissue microarray has enabled high-throughput pathology. Rather than the laborious review of individual slides and issues of assay reproducibility across large series of specimens, tissue microarrays allow the review of a single stain on a single slide containing tens to hundreds of samples. This is a paradigm shift in pathology, away from histomorphology and toward molecular characterization by immunohistochemistry. This platform allows large retrospective clinical studies of biomarkers… CONTINUE READING
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