Tissue manganese concentrations in lactating rats and their offspring following combined in utero and lactation exposure to inhaled manganese sulfate.

@article{Dorman2005TissueMC,
  title={Tissue manganese concentrations in lactating rats and their offspring following combined in utero and lactation exposure to inhaled manganese sulfate.},
  author={David Dorman and Anna M McElveen and Marianne W Marshall and Carl U. Parkinson and R. Arden James and Melanie F Struve and Brian A. Wong},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2005},
  volume={84 1},
  pages={12-21}
}
There is little information regarding the tissue distribution of manganese in neonates following inhalation. This study determined tissue manganese concentrations in lactating CD rats and their offspring following manganese sulfate (MnSO4) aerosol inhalation. Except for the period of parturition, dams and their offspring were exposed to air or MnSO4 (0.05, 0.5, or 1 mg Mn/m3) for 6 h/day, 7 days/week starting 28 days prior to breeding through postnatal day (PND) 18. Despite increased manganese… CONTINUE READING

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