Tissue levels of tumor necrosis factor-alpha correlates with grade of inflammation in untreated ulcerative colitis.

@article{Olsen2007TissueLO,
  title={Tissue levels of tumor necrosis factor-alpha correlates with grade of inflammation in untreated ulcerative colitis.},
  author={Trine Olsen and Rasmus Goll and Guanglin Cui and Anne Husebekk and Barthold Vonen and Grethe St\oa Birketvedt and Jon Florholmen},
  journal={Scandinavian journal of gastroenterology},
  year={2007},
  volume={42 11},
  pages={1312-20}
}
OBJECTIVE The immune characterization of ulcerative colitis (UC) has been unclear and controversial. One possible explanation for the discrepancies between earlier cytokine studies in UC may be the fact that the patients included were on immunosuppressive therapy. Thus, the aim of this study was to determine the tumor necrosis factor-alpha (TNF-alpha) level and T(H)1/T(H)2 cytokine expression (mRNA) profile in patients with untreated UC. MATERIAL AND METHODS Forty-four untreated UC patients… CONTINUE READING

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