Tissue insulin sensitivity and body weight in polycystic ovary syndrome.

  title={Tissue insulin sensitivity and body weight in polycystic ovary syndrome.},
  author={Philippa Marsden and Alison P. Murdoch and Roy Taylor},
  journal={Clinical endocrinology},
  volume={55 2},
OBJECTIVE Polycystic ovarian syndrome (PCOS) and obesity both affect insulin sensitivity. This study was designed to investigate the biochemical indices of PCOS and tissue insulin sensitivity in groups of lean and obese women with clinically equivalent degrees of the syndrome, relative to control subjects. DESIGN A prospective study of in vivo parameters and in vitro study of adipocytes to assess insulin sensitivity. PATIENTS Six lean and 14 overweight patients fulfilling formal diagnostic… CONTINUE READING
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