Tissue inhibitor of metalloproteinases-1 attenuates spontaneous liver fibrosis resolution in the transgenic mouse.

@article{Yoshiji2002TissueIO,
  title={Tissue inhibitor of metalloproteinases-1 attenuates spontaneous liver fibrosis resolution in the transgenic mouse.},
  author={Hitoshi Yoshiji and Shigeki Kuriyama and Junichi Yoshii and Yasuhide Ikenaka and Ryuichi Noguchi and Toshiya Nakatani and Hirohisa Tsujinoue and Koji Yanase and Tadashi Namisaki and Hiroo Imazu and Hiroshi Fukui},
  journal={Hepatology},
  year={2002},
  volume={36 4 Pt 1},
  pages={850-60}
}
It has been suggested that the tissue inhibitor of metalloproteinases-1 (TIMP-1) is involved in spontaneous resolution of liver fibrosis. The aim of this study was to investigate whether TIMP-1 altered spontaneous resolution of liver fibrosis in conjunction with matrix metalloproteinases (MMP) inhibition and hepatic stellate cell (HSC) activation. The… CONTINUE READING