Tissue inhibitor of metalloproteinase 1 activates normal human granulocytes, protects them from apoptosis, and blocks their transmigration during inflammation.

Abstract

Urinary levels of tissue inhibitor of metalloproteinase 1 (TIMP-1) higher than those of matrix metalloproteinase 9 (MMP-9) during acute pyelonephritis have previously been associated with a higher degree of acute inflammation and of postinfective renal scarring. The aim of the present study was to evaluate possible mechanisms by which TIMP-1 could affect… (More)

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Cite this paper

@article{Chromek2004TissueIO, title={Tissue inhibitor of metalloproteinase 1 activates normal human granulocytes, protects them from apoptosis, and blocks their transmigration during inflammation.}, author={Milan Chromek and Kjell Tullus and Joachim Lundahl and Annelie Brauner}, journal={Infection and immunity}, year={2004}, volume={72 1}, pages={82-8} }