Tissue hypoxia during fulminant hepatic failure

  title={Tissue hypoxia during fulminant hepatic failure},
  author={D. Bihari and A. Gimson and M. Waterson and R. Williams},
  journal={Critical Care Medicine},
  • D. Bihari, A. Gimson, +1 author R. Williams
  • Published 1985
  • Medicine
  • Critical Care Medicine
  • To assess the adequacy of tissue oxygenation in fulminant hepatic failure, we measured arterial oxygen delivery, the affinity of hemoglobin for oxygen, mixed venous oxygen tension, and lactate concentration in 32 patients suffering grade IV encephalopathy.In the patients who died, median systemic vascular resistance and oxygen extraction ratio were significantly (p < .005) lower than in those who survived (1268 vs. 1866 dyne. sec/cm5 m2 and 20% vs. 25%, respectively) despite a significantly (p… CONTINUE READING
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