Tissue growth and tumorigenesis in Drosophila: cell polarity and the Hippo pathway.


Cell polarity regulation is critical for defining membrane domains required for the establishment and maintenance of the apical-basal axis in epithelial cells (apico-basal polarity), asymmetric cell divisions, planar organization of tissues (planar cell polarity), and the formation of the front-rear axis in cell migration (front-rear polarity). In the… (More)
DOI: 10.1016/j.ceb.2017.03.006