Tissue growth and tumorigenesis in Drosophila: cell polarity and the Hippo pathway.

@article{Richardson2017TissueGA,
  title={Tissue growth and tumorigenesis in Drosophila: cell polarity and the Hippo pathway.},
  author={Helena E Richardson and Marta Portela},
  journal={Current opinion in cell biology},
  year={2017},
  volume={48},
  pages={1-9}
}
Cell polarity regulation is critical for defining membrane domains required for the establishment and maintenance of the apical-basal axis in epithelial cells (apico-basal polarity), asymmetric cell divisions, planar organization of tissues (planar cell polarity), and the formation of the front-rear axis in cell migration (front-rear polarity). In the vinegar fly, Drosophila melanogaster, cell polarity regulators also interact with the Hippo tissue growth control signaling pathway. In this… CONTINUE READING
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