Tissue factor procoagulant activity of plasma microparticles is increased in patients with early-stage prostate cancer.

@article{Haubold2009TissueFP,
  title={Tissue factor procoagulant activity of plasma microparticles is increased in patients with early-stage prostate cancer.},
  author={Katja Haubold and Michael Rink and Brigitte Spath and Martin Friedrich and Felix Kyoung-Hwan Chun and Guy Marx and Ali Amirkhosravi and John L. Francis and Carsten Bokemeyer and Barbara Eifrig and F. Descarries-Be Langer},
  journal={Thrombosis and haemostasis},
  year={2009},
  volume={101 6},
  pages={
          1147-55
        }
}
Tissue factor (TF) plays a critical role in tumour growth and metastasis, and its enhanced release into plasma in association with cellular microparticles (MPs) has recently been associated with pathological cancer progression. We have previously demonstrated significantly elevated levels of plasma TF antigen as well as systemic coagulation and platelet activation in patients with localised prostate cancer. In this prospective study, we used a highly sensitive one-stage clotting assay to… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 39 CITATIONS

Plasma microparticles in patients with gynaecological malignancy

VIEW 8 EXCERPTS
CITES RESULTS, BACKGROUND & METHODS
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 45 REFERENCES

Plasma tissue factor antigen in localized prostate cancer: distribution, clinical significance and association with hemostatic activation markers

F Langer, KHF Chun, A Amirkhosravi
  • Thromb Haemost
  • 2007
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Cancer-associated thrombosis.

  • Critical reviews in oncology/hematology
  • 2006
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Contribution of host-derived tissue factor to tumor neovascularization.

  • Arteriosclerosis, thrombosis, and vascular biology
  • 2008
VIEW 1 EXCERPT

Mechanisms of thrombus formation.

  • The New England journal of medicine
  • 2008
VIEW 1 EXCERPT