Tissue factor pathway inhibitor concentrations in cirrhotic patients with and without portal vein thrombosis.

@article{Okszoglu1997TissueFP,
  title={Tissue factor pathway inhibitor concentrations in cirrhotic patients with and without portal vein thrombosis.},
  author={G{\"u}rol Oks{\"u}zoglu and Halis Şimşek and Ibrahim Celalettin Haznedaroğlu and Serafettin Kirazli},
  journal={The American journal of gastroenterology},
  year={1997},
  volume={92 2},
  pages={303-6}
}
OBJECTIVES Our aim was to determine whether tissue factor pathway inhibitor (TFPI), a physiologically important natural anticoagulant that acts by inhibiting the extrinsic pathway, concentrations decrease as liver disease progresses, and, second, whether TFPI has an etiologic role in portal vein thrombosis in cirrhotics. METHODS After taking their informed consent, we determined TFPI concentrations in the plasma of healthy subjects (group I) (n = 15) (average age, 45.1 = 11.8 yr), cirrhotics… CONTINUE READING