Tissue factor modulates the thrombogenicity of human atherosclerotic plaques.

  title={Tissue factor modulates the thrombogenicity of human atherosclerotic plaques.},
  author={Vincenzo Toschi and Richard M. Gallo and Maddalena Lettino and John T. Fallon and S. David Gertz and Antonio Fern{\'a}ndez-Ort{\'i}z and James H. Chesebro and Lina Badimon and Yale Nemerson and Valentin Fuster and Juan Jose Badimon},
  volume={95 3},
BACKGROUND The thrombogenicity of a disrupted atherosclerotic lesion is dependent on the nature and extent of the plaque components exposed to flowing blood together with local rheology and a variety of systemic factors. We previously reported on the different thrombogenicity of the various types of human atherosclerotic lesions when exposed to flowing blood in a well-characterized perfusion system. This study examines the role of tissue factor in the thrombogenicity of different types of… CONTINUE READING


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