Tissue factor is an angiogenic-specific receptor for factor VII-targeted immunotherapy and photodynamic therapy

@inproceedings{Hu2016TissueFI,
  title={Tissue factor is an angiogenic-specific receptor for factor VII-targeted immunotherapy and photodynamic therapy},
  author={Zhiwei Hu and Jijun Cheng and Jie Xu and Wolfram Ruf and Charles Joseph Lockwood},
  booktitle={Angiogenesis},
  year={2016}
}
Identification of target molecules specific for angiogenic vascular endothelial cells (VEC), the inner layer of pathological neovasculature, is critical for discovery and development of neovascular-targeting therapy for angiogenesis-dependent human diseases, notably cancer, macular degeneration and endometriosis, in which vascular endothelial growth factor (VEGF) plays a central pathophysiological role. Using VEGF-stimulated vascular endothelial cells (VECs) isolated from microvessels, venous… CONTINUE READING

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