Tissue factor-bearing exosome secretion from human mechanically stimulated bronchial epithelial cells in vitro and in vivo

@article{Park2012TissueFE,
  title={Tissue factor-bearing exosome secretion from human mechanically stimulated bronchial epithelial cells in vitro and in vivo},
  author={Jin-Ah Park and Asma S. Sharif and Daniel J Tschumperlin and Laurie CK Lau and Rachel Limbrey and Peter Howarth and Jeffrey M Drazen},
  journal={The Journal of allergy and clinical immunology},
  year={2012},
  volume={130 6},
  pages={1375-83}
}
BACKGROUND Tissue factor (TF), a primary initiator of blood coagulation, also plays a pivotal role in angiogenesis. TF expression in the airways is associated with asthma, a disease characterized in part by subepithelial angiogenesis. OBJECTIVES To determine potential sources of TF and the mechanisms of its availability in the lung microenvironment. METHODS Normal human bronchial epithelial cells grown in air-liquid interface culture were subjected to a compressive stress of 30 cm H(2)O… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 47 references

The influence of bronchoconstrictiononairway remodeling inasthma

CL Grainge, LC Lau, +3 authors S Wilson
NEngl JMed • 2011

Induction of tissue factor by urokinase in lung epithelial cells and in the lungs.

American journal of respiratory and critical care medicine • 2010
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