Tissue factor and monocyte chemoattractant protein-1 expression in hypertensive individuals with normal or increased carotid intima-media wall thickness.

@article{Sardo2008TissueFA,
  title={Tissue factor and monocyte chemoattractant protein-1 expression in hypertensive individuals with normal or increased carotid intima-media wall thickness.},
  author={Maria Adriana Sardo and Salvatore Campo and Giuseppe Mandraffino and Carlo Saitta and Antonio Bonaiuto and Maria Castaldo and Maurizio Cinquegrani and Giovanni Pizzimenti and Antonino Saitta},
  journal={Clinical chemistry},
  year={2008},
  volume={54 5},
  pages={814-23}
}
BACKGROUND People with hypertension display an inflammatory pattern that includes increased plasma concentrations of monocyte chemoattractant protein 1 (MCP-1) and C-reactive protein (CRP) and enhanced expression of tissue factor (TF) mRNA in blood monocytes. METHODS In this study, we investigated the relationship between CRP concentrations and TF and MCP-1 mRNA expression in unstimulated and lipopolysaccharide (LPS)-stimulated monocytes isolated from hypertensives with or without an increase… CONTINUE READING