Tissue factor activity of blood mononuclear cells is increased after total knee arthroplasty.

@article{Johnson2009TissueFA,
  title={Tissue factor activity of blood mononuclear cells is increased after total knee arthroplasty.},
  author={Gerhard J. Johnson and Linda A. Leis and Ronald R. Bach},
  journal={Thrombosis and haemostasis},
  year={2009},
  volume={102 4},
  pages={
          728-34
        }
}
Tissue factor (TF) is present in small quantities in normal blood and is reported to be elevated in arterial and venous thrombosis. Patients undergoing total knee arthoplasty (TKA) are at high risk of post-operative venous thromboembolism (VTE). To evaluate the possible contribution of elevated blood TF to VTE risk, we performed serial studies of peripheral blood mononuclear cell (PBMC) functional TF procoagulant activity (PCA) in 19 patients after TKA. PBMC and platelet TF PCA were measured by… CONTINUE READING

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