Tissue expression of four troponin I genes and their molecular interactions with two troponin C isoforms in Caenorhabditis elegans.

@article{Ruksana2005TissueEO,
  title={Tissue expression of four troponin I genes and their molecular interactions with two troponin C isoforms in Caenorhabditis elegans.},
  author={Razia Ruksana and Kazuki Kuroda and Hiromi Terami and Tetsuya Bando and Shun Kitaoka and Tomohide Takaya and Yasuji Sakube and Hiroaki Kagawa},
  journal={Genes to cells : devoted to molecular & cellular mechanisms},
  year={2005},
  volume={10 3},
  pages={261-76}
}
Gene duplication is a major genetic event that can produce multiple protein isoforms. Comparative sequence and functional analysis of related gene products can provide insights into protein family evolution. To characterize the Caenorhabditis elegans troponin I family, we analyzed gene structures, tissue expression patterns and RNAi phenotypes of four troponin I isoforms. Tissue expression patterns were determined using lacZ/gfp/rfp reporter gene assays. The tni-1, tni-2/unc-27 and tni-3 genes… CONTINUE READING