Tissue engineering of the intestine in a murine model.

  title={Tissue engineering of the intestine in a murine model.},
  author={Erik R. Barthel and Allison L. Speer and Daniel E. Levin and Frederic Sala and Xiaogang Hou and Yasuhiro Torashima and Clarence M Wigfall and Tracy C Grikscheit},
  journal={Journal of visualized experiments : JoVE},
Tissue-engineered small intestine (TESI) has successfully been used to rescue Lewis rats after massive small bowel resection, resulting in return to preoperative weights within 40 days.(1) In humans, massive small bowel resection can result in short bowel syndrome, a functional malabsorptive state that confers significant morbidity, mortality, and healthcare costs including parenteral nutrition dependence, liver failure and cirrhosis, and the need for multivisceral organ transplantation.(2) In… CONTINUE READING
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