Tissue engineering of human cartilage and osteochondral composites using recirculation bioreactors.

@article{Mahmoudifar2005TissueEO,
  title={Tissue engineering of human cartilage and osteochondral composites using recirculation bioreactors.},
  author={Nastaran Mahmoudifar and Pauline M Doran},
  journal={Biomaterials},
  year={2005},
  volume={26 34},
  pages={7012-24}
}
Chondrocytes isolated from human foetal epiphyseal cartilage were seeded dynamically into polyglycolic acid (PGA) scaffolds and cultured in recirculation column bioreactors to produce tissue-engineered cartilage. Several culture techniques with the potential to provide endogenous growth factors and other conditions beneficial for de novo cartilage synthesis were investigated. Osteochondral composite constructs were generated by seeding separate PGA scaffolds with either foetal chondrocytes or… CONTINUE READING

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