Tissue engineering of autologous cartilage for craniofacial reconstruction by injection molding.

@article{Chang2003TissueEO,
  title={Tissue engineering of autologous cartilage for craniofacial reconstruction by injection molding.},
  author={Sophia Chia-Ning Chang and Geoffrey Tobias and Amit Kr. Roy and Charles A. Vacanti and Lawrence J. Bonassar},
  journal={Plastic and reconstructive surgery},
  year={2003},
  volume={112 3},
  pages={
          793-9; discussion 800-1
        }
}
Each year, more than one million patients undergo some type of procedure involving cartilage reconstruction. Polymer hydrogels such as alginate have been demonstrated to be effective carriers of chondrocytes for subcutaneous cartilage formation. The goal of this study was to develop a simple method to create complex structures with good three-dimensional tolerance in order to form cartilage in specific shapes in an autologous animal model. Six alginate implants that had been seeded with… CONTINUE READING
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