Tissue engineering applications in the management of bone loss.

@article{Carulli2013TissueEA,
  title={Tissue engineering applications in the management of bone loss.},
  author={Christian Carulli and Fabrizio Matassi and Roberto Civinini and Massimo Innocenti},
  journal={Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases},
  year={2013},
  volume={10 1},
  pages={
          22-5
        }
}
Several conditions in Orthopaedics and Traumatology are characterized by a bone loss. Bone auto- or allo-grafting was considered sufficient to fullfill the defects decades ago; however, large bone defects were challenging for the Surgeons, particularly in case of necessity of structural and biological properties. Bioindusrty proposed over the years synthetic biomaterials, as Demineralized Bone Matrix, bioactive surfaces for implant coponents, and recently recombinant Bone Morphogenetic Proteins… CONTINUE READING

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