Tissue-engineered three-dimensional tumor models to study tumor angiogenesis.

  title={Tissue-engineered three-dimensional tumor models to study tumor angiogenesis.},
  author={Scott S. Verbridge and E Mitchell Chandler and Claudia Fischbach},
  journal={Tissue engineering. Part A},
  volume={16 7},
Cell-microenvironment interactions play a critical role in the transformation of normal cells into cancer; however, the underlying mechanisms and effects are far from being well understood. Tissue Engineering provides innovative culture tools and strategies to study tumorigenesis under pathologically relevant culture conditions. Specifically, integration of biomaterials, scaffold fabrication, and micro/nano-fabrication techniques offers great promise to reveal the dynamic role of chemical, cell… CONTINUE READING