Tissue-engineered small intestine improves recovery after massive small bowel resection.

  title={Tissue-engineered small intestine improves recovery after massive small bowel resection.},
  author={Tracy C Grikscheit and A. R. Shoyeb Ahmed Siddique and Erin Rubin Ochoa and Ashok Srinivasan and Eben Alsberg and Richard Aaron Hodin and Joseph Phillip Vacanti},
  journal={Annals of surgery},
  volume={240 5},
OBJECTIVE Rescue with tissue-engineered small intestine (TESI) after massive small bowel resection (MSBR). SUMMARY BACKGROUND DATA Short bowel syndrome is a morbid product of massive small bowel resection. We report the first replacement of a vital organ by tissue engineering with TESI after MSBR. METHODS Ten male Lewis rats underwent TESI implantation with green fluorescent protein (GFP)-marked cells (TESI+, n = 5) or sham laparotomy (TESI-, n = 5) followed by MSBR. Side-to-side… CONTINUE READING
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