Tissue-engineered bone formation using human bone marrow stromal cells and novel beta-tricalcium phosphate.

Abstract

In this study we investigated not only the cellular proliferation and osteogenic differentiation of human bone marrow stromal cells (hBMSCs) on the novel beta-tricalcium phosphate (beta-TCP) scaffolds in vitro but also bone formation by ectopic implantation in athymic mice in vivo. The interconnected porous beta-TCP scaffolds with pores of 300-500 microm in… (More)
DOI: 10.1088/1748-6041/2/2/004

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