Tissue distribution of lignans in rats in response to diet, dose-response, and competition with isoflavones.

@article{Murray2007TissueDO,
  title={Tissue distribution of lignans in rats in response to diet, dose-response, and competition with isoflavones.},
  author={Timothy E Murray and Jinguo Kang and Lee Astheimer and William Evan Price},
  journal={Journal of agricultural and food chemistry},
  year={2007},
  volume={55 12},
  pages={4907-12}
}
This paper investigates the occurrence and distribution of the lignan metabolites enterodiol (END) and enterolactone (ENL) and the isoflavone daidzein (DAID) in rat tissues by use of liquid chromatography-electrospray ionization mass spectrometry (LC-ESI/MSn) following a variety of dietary regimes. Furthermore, we examined the dose-response and distribution of END and ENL in liver, testes, prostate, and lung, and we investigated the effects of competition between lignans and isoflavones on… CONTINUE READING