Tissue distribution of isoflavones in ewes after consumption of red clover silage.

@article{UrpiSard2008TissueDO,
  title={Tissue distribution of isoflavones in ewes after consumption of red clover silage.},
  author={Mireia Urpi-Sard{\`a} and Christine Morand and Catherine Besson and Guillaume Kraft and Didier Viala and Augustin Scalbert and J M Besle and Claudine Manach},
  journal={Archives of biochemistry and biophysics},
  year={2008},
  volume={476 2},
  pages={205-10}
}
When discovered in the 50's, isoflavones were suspected to provoke infertility syndrome in sheep grazing on clover. Many others effects of these phytoestrogens have been documented afterwards. To determine the distribution of isoflavone metabolites in ewe tissues and look for a link with their physiological impact, two ewes were fed a diet containing 50% red clover silage (variety Pawera) for one month with a daily intake of 157.6 mg/kg bw of total isoflavones. Only aglycones were fed due to… CONTINUE READING