Tissue distribution of intravenously injected dinitrophenylated human serum albumin. Effects of specific IgG and IgA antibodies.

  • Thomas Skogh
  • Published 1982 in Scandinavian journal of immunology
After intravenous injection into mice, human serum albumin (HSA) substituted with 35 dinitrophenyl (DNP) groups per molecule rapidly became deposited on and endocytosed by non-parenchymal liver cells. Much was also found outside the reticuloendothelial system, e.g. in heart and skeletal muscle. The relative amount of circulating DNP35HSA taken up diminished… CONTINUE READING