Tissue distribution and putative physiological function of NOX family NADPH oxidases.

@article{Krause2004TissueDA,
  title={Tissue distribution and putative physiological function of NOX family NADPH oxidases.},
  author={Karl-Heinz Krause},
  journal={Japanese journal of infectious diseases},
  year={2004},
  volume={57 5},
  pages={S28-9}
}
The NOX family of ROS-generating NADPH oxidases consists of 7 members: NOX1 to NOX5, DUOX1 and 2. NOX1 is predominantly found in the colon, where it possibly plays a role in the host defense. NOX2 is the phagocyte NADPH oxidase, a clearly established host defense enzyme. NOX3 is almost exclusively expressed in the inner ear, where it is involved in otoconia morphogenesis, but based on its localization might also play a role in the auditory system. NOX4, widely expressed in kidney, vascular… CONTINUE READING