Tissue-derived mesenchymal stromal cells used as vehicles for anti-tumor therapy exert different in vivo effects on migration capacity and tumor growth

@inproceedings{BelmarLopez2013TissuederivedMS,
  title={Tissue-derived mesenchymal stromal cells used as vehicles for anti-tumor therapy exert different in vivo effects on migration capacity and tumor growth},
  author={Carolina Belmar-Lopez and Gracia Mendoza and Daniel Oberg and Jerome Burnet and Carlos Sim{\'o}n and Irene Cervell{\'o} and Maite Iglesias and Juan Carlos Caravantes Ram{\'i}rez and Pilar L{\'o}pez-Larrubia and Miguel Quintanilla and Pilar Mart{\'i}n-Duque},
  booktitle={BMC medicine},
  year={2013}
}
BACKGROUND Mesenchymal stem cells (MSCs) have been promoted as an attractive option to use as cellular delivery vehicles to carry anti-tumor agents, owing to their ability to home into tumor sites and secrete cytokines. Multiple isolated populations have been described as MSCs, but despite extensive in vitro characterization, little is known about their in vivo behavior.The aim of this study was to investigate the efficacy and efficiency of different MSC lineages derived from five different… CONTINUE READING
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Immunosuppressive properties of mesenchymal stem cells: advances and applications

  • MP De Miguel, S Fuentes-Julian, +4 authors F Arnalich-Montiel
  • Curr Mol Med
  • 2012
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