Tissue deformation modulates twist expression to determine anterior midgut differentiation in Drosophila embryos.

Abstract

Mechanical deformations associated with embryonic morphogenetic movements have been suggested to actively participate in the signaling cascades regulating developmental gene expression. Here we develop an appropriate experimental approach to ascertain the existence and the physiological relevance of this phenomenon. By combining the use of magnetic tweezers… (More)
DOI: 10.1016/j.devcel.2008.07.009

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