Tissue concentrations of mezlocillin in benign hypertrophy of the prostate following intravenous bolus injection versus infusion.

In 23 patients undergoing transurethral resection or suprapubic operation of benign hypertrophy of the prostate, perioperative antibiotic prophylaxis was started with 5 g of mezlocillin in each patient. In five patients (group I) the antibiotic was given as an intravenous bolus. In five patients (group II) mezlocillin was administered as a bolus of 1 g… CONTINUE READING