Tissue concentration and urinary excretion pattern of sulfofluorescein by the rat kidney.

@article{Ammer1993TissueCA,
  title={Tissue concentration and urinary excretion pattern of sulfofluorescein by the rat kidney.},
  author={Ulrich Ammer and Y u Natochin and Karl J. Ullrich},
  journal={Journal of the American Society of Nephrology : JASN},
  year={1993},
  volume={3 8},
  pages={
          1474-87
        }
}
In order to find a fluorescein analog that is excreted in a way similar to p-aminohippurate (PAH) and is suitable to register excretion into the urine and also to monitor continuously the concentration within cortical tissue, the interference of fluorescein, sulfofluorescein (SF), and fluorescein-5(6)-sulfonate with the contraluminal transport systems of PAH, succinate, and sulfate and with the luminal transport system of sulfate and lactate was evaluated. All three substances exerted a strong… CONTINUE READING