Tissue-based map of the human proteome

@article{Uhln2015TissuebasedMO,
  title={Tissue-based map of the human proteome},
  author={M. Uhl{\'e}n and L. Fagerberg and B. Hallstr{\"o}m and C. Lindskog and P. Oksvold and A. Mardinoglu and {\AA}sa Sivertsson and C. Kampf and E. Sj{\"o}stedt and A. Asplund and Ingmarie Olsson and K. Edlund and E. Lundberg and Sanjay Navani and Cristina Al-Khalili Szigyarto and J. Odeberg and D. Djureinovic and Jenny Ottosson Takanen and S. Hober and T. Alm and P. Edqvist and Holger Berling and H. Tegel and J. Mulder and J. Rockberg and P. Nilsson and J. Schwenk and Marica Hamsten and Kalle von Feilitzen and Mattias Forsberg and L. Persson and Fredric Johansson and Martin Zwahlen and G. von Heijne and J. Nielsen and F. Pont{\'e}n},
  journal={Science},
  year={2015},
  volume={347}
}
  • M. Uhlén, L. Fagerberg, +33 authors F. Pontén
  • Published 2015
  • Biology, Medicine
  • Science
  • Protein expression across human tissues Sequencing the human genome gave new insights into human biology and disease. However, the ultimate goal is to understand the dynamic expression of each of the approximately 20,000 protein-coding genes and the function of each protein. Uhlén et al. now present a map of protein expression across 32 human tissues. They not only measured expression at an RNA level, but also used antibody profiling to precisely localize the corresponding proteins. An… CONTINUE READING

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