Tissue and subcellular distributions of the smg-21/rap1/Krev-1 proteins which are partly distinct from those of c-ras p21s.

@article{Kim1990TissueAS,
  title={Tissue and subcellular distributions of the smg-21/rap1/Krev-1 proteins which are partly distinct from those of c-ras p21s.},
  author={Sang Jin Kim and Akira Mizoguchi and Akira Kikuchi and Yoshimi Takai},
  journal={Molecular and cellular biology},
  year={1990},
  volume={10 6},
  pages={
          2645-52
        }
}
We have made a specific antiserum recognizing both smg p21A (the rap1A/Krev-1 protein) and -B (the rap1B protein), ras p21-like GTP-binding proteins having the same putative effector domain as ras p21s and have used this antiserum to study the tissue and subcellular distributions of smg p21s by immunoblot and immunocytochemical analyses. By immunoblot analysis, smg p21s were detected in various rat tissues and at the highest level in brain. By light microscopic immunocytochemical analysis, smg… CONTINUE READING
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