Tissue Response to Subcutaneously Implanted Recombinant Spider Silk: An in Vivo Study

@inproceedings{Fredriksson2009TissueRT,
  title={Tissue Response to Subcutaneously Implanted Recombinant Spider Silk: An in Vivo Study},
  author={Camilla Fredriksson and My Hedhammar and Ricardo Feinstein and Kerstin Nordling and Gunnar Kratz and Jan Thomas Johansson and Fredrik Huss and Anna Rising},
  year={2009}
}
Spider silk is an interesting biomaterial for medical applications. Recently, a method for production of recombinant spider silk protein (4RepCT) that forms macroscopic fibres in physiological solution was developed. Herein, 4RepCT and Mersilk (control) fibres were implanted subcutaneously in rats for seven days, without any negative systemic or local reactions. The tissue response, characterised by infiltration of macrophages and multinucleated cells, was similar with both fibres, while only… CONTINUE READING

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