Tissue Repair: An Important Determinant of Final Outcome of Toxicant-Induced Injury

@article{Mehendale2005TissueRA,
  title={Tissue Repair: An Important Determinant of Final Outcome of Toxicant-Induced Injury},
  author={Harihara M. Mehendale},
  journal={Toxicologic Pathology},
  year={2005},
  volume={33},
  pages={41 - 51}
}
  • H. Mehendale
  • Published 1 January 2005
  • Biology, Medicine
  • Toxicologic Pathology
Tissue repair is a dynamic compensatory cell proliferation and tissue regeneration response stimulated in order to overcome acute toxicity and recover organ/tissue structure and function. Extensive evidence in rodent models using structurally and mechanistically diverse hepatotoxicants such as acetaminophen (APAP), carbon tetrachloride (CCl4), chloroform (CHCl3), thioacetamide (TA), trichloroethylene (TCE), and allyl alcohol (AA) have demonstrated that tissue repair plays a critical role in… Expand
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